Calcineurin Regulates Myocardial Function during Acute Endotoxemia
نویسندگان
چکیده
منابع مشابه
Calcineurin regulates myocardial function during acute endotoxemia.
RATIONALE Cyclosporin A (CsA) is known to preserve cardiac contractile function during endotoxemia, but the mechanism is unclear. Increased nitric oxide (NO) production and altered mitochondrial function are implicated as mechanisms contributing to sepsis-induced cardiac dysfunction, and CsA has the capacity to reduce NO production and inhibit mitochondrial dysfunction relating to the mitochond...
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ژورنال
عنوان ژورنال: American Journal of Respiratory and Critical Care Medicine
سال: 2006
ISSN: 1073-449X,1535-4970
DOI: 10.1164/rccm.200411-1507oc